3.00 p.m. Registration
4.00 p.m. Lecture 1

Richard Morris
"Introduction to Mouse Transgenics and Behaviour"

Tuesday 17 August

9.00 a.m. Lecture 2

Rick Lathe
"Techniques for the Transgenic Manipulation of Mice"

10.00 a.m. Coffee break (and immediate continuation of lecture)
11.00 a.m. Lecture 3

Derek Rogers
"SHIRPA – A Comprehensive Behavioural Characterisation of the Phenotype of Mouse Mutation"

12.20 p.m. Lunch
1.00 p.m. Laboratory work
5.30 p.m. Question-and-Answer session with Rick Lathe and Derek Rogers
6.30 - Wine, Cheese and Posters.
7.30 p.m. First Poster Session – Posters of Barco to Kôks.

Wednesday 18 August

9.00 a.m. Lecture 4

Tim Bliss
"Neurogenetic strategies in the study of synaptic plasticity, learning and memory"

10.20 a.m. Coffee break
10.40 a.m. Lecture 5

Lucia Jacobs
"The ecology and evolution of hippocampal function"

12.00 noon Lunch
12.30 p.m. Laboratory work
5.30 p.m. Question-and-Answer session with Tim Bliss and Lucia Jacobs
6.30 p.m. Laboratory work (as required)

Thursday 19 August

9.00 a.m. Lecture 6

Seth Grant
"The NMDA receptor-PSD95 multi-protein signalling complex: a central mechanism for the induction of synaptic plasticity"

10.20 a.m. Coffee break
10.40 a.m. Lecture 7

Isabelle Mansuy
"A genetic approach to the role of calcineurin in synaptic plasticity, learning and memory"

12.00 noon Lunch
12.30 p.m. Laboratory work
5.30 p.m. Question-and-Answer session with Seth Grant and Isabelle Mansuy
6.30 p.m. Laboratory work (as required)

Friday 20 August

9.00 a.m. Lecture 8

Howard Eichenbaum (unable to attend. Proxy: Emma Wood)
"Hippocampal function with a focus on single unit recording"

10.20 a.m. Coffee break
10.40 a.m. Lecture 9

Karl-Peter Giese
"The use of targeted point mutants in the study of learning and memory"

12.00 noon Lunch
12.30 p.m. Laboratory work
5.30 p.m. Question-and-answer session with Howard Eichenbaum and Karl-Peter Giese
6.30 p.m. Laboratory work (as required)

Saturday 21 August

9.00 a.m. Lecture 10

Jacques Micheau
"Modelling human memory in mice: a challenge to cognitive neuroscientists"

10.20 a.m. Coffee break
10.40 a.m. Laboratory work

Sunday 22 August

REST DAY

Monday 23 August

9.00 a.m. Lecture 11 and Discussion Groups

Neil Watt and Paul Flecknall
"Science and Society: the legal ethical and pragmatic issues involved in the design and conduct of animal experiments"

10.20 a.m. Coffee break
10.40 a.m. Watt and Flecknall - continued
12.00 noon Lunch
12.30 p.m. Laboratory work
5.30 p.m. Lecture 12

Rick Lathe
"All that glisters is not gold – genes, transgenesis and behavior"

Tuesday 24 August

9.00 a.m. Lecture 13

Paul Chapman
"Transgenic models of human degenerative disease"

10.20 a.m. Coffee break
10.40 a.m. Lecture 14

Gerry Dawson and Lawrence Wilkinson
"Assessing learning and memory in transgenic mice: No cause for anxiety" and

"Applying operant methods to mouse behaviour with particular reference to visuospatial attentional functioning"

12.30 p.m. Lunch
1.00 p.m. Laboratory work
5.30 p.m. Question-and-Answer session with Paul Chapman, Gerry Dawson and Lawrence Wilkinson
6.30 p.m. Wine, Cheese & Posters
Second Poster Session (Lemberger to Honkanen of above list)

Wednesday 25 August

9.00 a.m. Lecture 15

David Wolfer
"Is it the Mutation or the Genetic Background? Lessons from Meta-Analysis of Water-Maze Experiments"
Additionally: Slides in PDF-format

10.20 a.m. Coffee break
10.40 a.m. Lecture 16

Hans-Peter Lipp
"Beyond the rim of Morris’ maze: targeted gene deletions, thigmotaxis, mossy fibres and ecological brain research"

12.00 noon Lunch
12.30 p.m. Laboratory work
5.30 p.m. Question-and-Answer session with Hans-Peter Lipp, David Wolfer and Richard Morris
6.30 p.m. Laboratory work (as required)

Thursday 26 August

9.00 a.m. Lecture 17

Barry Keverne
"Genomic Imprinting, Brain Development and Behaviour"

10.20 a.m. Coffee break
10.40 a.m. Lecture 18

John Mullins
"Using transgenic animals to study cardiovascular disease" (no abstract)

12.00 noon Lunch
12.30 p.m. Laboratory work
5.30 p.m. Question-and-Answer session with Barry Keverne and John Mullins
6.30 p.m. Laboratory work (as required)

Friday 27 August

9.00 a.m. All day for completion of laboratory work, data-analysis, preparation of project group presentations of overheads etc. for talks on Saturday.

Saturday 28 August

9.00 a.m. Presentation of results from the Projects.
All presentations to be 20 mins (approx) + 10 mins for questions
9.00 a.m. Project A
9.30 a.m. Project B
10.00 a.m. Project C
10.30 a.m. Project D
11.00 a.m. Coffee break
11.20 a.m. Richard Morris and David Wolfer

"Overview of course, feedback from students, recommendations for any future course"